Azithromycin Electrochemical Determination Using Vanadium Dioxide as Cathodic Material

A novel modified electrode based on a vanadium dioxide (VO2) thin film was developed for the sensitive determination and to detect azithromycin (AZI) antibiotic. VO2 films were prepared by hydrothermal synthesis. The electrochemical properties of estimated using voltammetric techniques. reaction between AZI resulted in considerable shift anodic peak current AZI. limit detection sensitivity proposed procedure also evaluated. study performed square-wave voltammetry, cyclic voltammetry scan rate variation. suggested showed good stability determination, with an analytical curve different concentration 1.0–80 μmol L−1. Under concentrations AZI, values found quantification 2.12 0.64 mmol L−1 (in synthetic urine samples) 42.5 14 (milk samples), respectively. Moreover, it demonstrated that simple combination, PET/ITO/VO2 could be optional system applications analysis pharmaceutical products, aquatic environments, clinical samples (urine) or examine food quality